Berberine Complex (formerly Berberine)

Neurobiologix Berberine Complex (formerly Berberine) 

Metabolism & Glucose Support 

Berberine Complex supports cardiometabolic health with a powerful, synergistic combination, featuring 400 mg of berberine per capsule enhanced with alpha-lipoic acid (ALA) and supported by biotin and chromium. This specialized formulation is designed to help optimize glucose and insulin metabolism, hemoglobin A1c (HbA1c) levels, cardiovascular health, and weight management.

Key Benefits: 

• May Help Regulate Glucose Levels
• Supports Healthy Blood Sugar Metabolism 
• Promotes Cardiovascular Health
• Supports Healthy Lipid Metabolism

Ingredients 

Serving Size: 1 Vegetarian Capsule	Amount/Serving
Biotin (as D-Biotin)	200 mcg
Chromium (as chromium picolinate)	200 mcg
Berberine (as Berberine HCI)(Berberis aristata)(root)	400 mg
Alpha Lipoic Acid	100 mg

Other Ingredients: Methylcellulose Capsule, Microcrystalline Cellulose. 

Vegetarian, Gluten-Free, Non-GMO 

Suggested Use

Take 1 capsule twice daily with a meal, or as directed by your healthcare practitioner.

Warning: Not recommended for pregnant or lactating women. Keep out of reach of children. 

Storage: Keep in a cool, dry place. 

More Info. 

The increasing prevalence of obesity, nutrient-sparse and calorie-dense foods, sedentary lifestyles, and chronic stress all contribute to cardiometabolic disturbances that undermine the healthspan and vitality of young and mature adults alike. The botanical ingredient berberine has emerged as one of the most promising natural products to support cardiometabolic pathways. When paired with alpha-lipoic acid, these ingredients work together via complementary mechanisms to help optimize clinical results. Biotin and chromium provide added synergy for a well-rounded, yet targeted approach to optimizing cardiometabolic wellness.

Berberine

Berberine is an active alkaloid derived from the Berberis aristata plant, among others. It has a long history of use in traditional Chinese and Indian medicinal practices, and modern science confirms its impressive health benefits, particularly in the areas of blood sugar, metabolism, and adipogenesis/weight loss.1 Research attributes berberine’s effects to key mechanisms, including: 

Gene Expression Regulator

In vitro research suggests that berberine suppresses adipogenesis via inhibiting the activities of cAMP-responsive element-binding protein (CREB) and CCAAT/enhancer-binding protein (C/EBP)β. This interaction leads to decreased expression of adipogenic genes, including peroxisome proliferator-activated receptor gamma2 (PPAR-gamma2).

AMPK Activator 

Berberine activates an important enzyme in the body called AMPK (adenosine monophosphate-activated protein kinase),  which plays a central role in energy balance and metabolic function. By activating AMPK in adipocytes and muscle cells, berberine is thought to help the body burn fat more efficiently, reduce fat accumulation, and improve insulin sensitivity and glucose uptake.

Human studies have validated in vitro and preclinical mechanistic research, demonstrating that oral doses of berberine can improve cardiometabolic health parameters: decrease weight; improve blood pressure, blood lipids, and total insulin secretion; lower hemoglobin A1C (HbA1c); and increase insulin sensitivity.

Alpha-Lipoic Acid  

Alpha-lipoic acid (ALA) may enhance the cardiometabolic benefits of berberine through complementary mechanisms that result in significant effects on fasting glucose, insulin sensitivity, HbA1c, and lipid profiles. ALA is a powerful antioxidant that raises glutathione levels and regenerates other antioxidants, including vitamins E and C. It is also a cofactor for mitochondrial energy production, activates peripheral AMPK, and regulates gene transcription of PPARalpha and PPAR-gamma, which are involved in glucose and lipid metabolism.

Chromium and Biotin

These micronutrients play essential roles in regulating glucose and lipid metabolism, insulin effectiveness, and the expression of genes important for metabolism. Their combined supplementation has shown promising results on improving glycemic control, HbA1c levels, and lipid measurements in individuals taking oral glucose medications. These clinical findings support in vitro and animal data demonstrating that chromium and biotin have greater effects on glucose disposal and lipid metabolism when combined.

Neurobiologix's Product Commitment:

• Formulated by Physicians
• Crafted for Maximum Potency, Purity & Absorption 
• 35+ Custom Supplements Designed by Genetic Experts
• Manufactured in FDA-Certified, cGMP Facilities
• Third-Party Tested for Safety & Efficacy
• Designed to Support Common Genetic Variants 

Neurobiologix is dedicated to crafting the highest-quality professional-grade supplements and pairing them with personalized, science-backed protocols designed to extend health spans, elevate well-being, and help people feel their best at every age and stage of life.

With less than 3% of products on the market meeting professional-grade standards, Neurobiologix prioritizes delivering the purest form of nutrients for the best possible health outcomes.