Sleep & Perform
Xymogen Sleep & Perform
Sleep Tonight, Function Tomorrow
Sleep & PerformĀ features ShodenĀ®, an ashwagandha extract with demonstrated benefits for supporting the restoration of sleep quality. Complemented with a proprietary blend of spearmint and green tea extract, this formula is designed to promote restful sleep and bolster daytime performance.
Key Benefits and Features:Ā
- Promotes Restful Sleep
- Supports Daytime Focus and Concentration
- Improves Sleep Quality and Next-Day Cognitive Function
Ingredients
| Serving Size: 2 Capsules | Amount/Serving |
| Magnesium (as magnesium bisglycinate chelate)Ā | 50 mg |
| Proprietary Blend | 485 mg |
| Spearmint Extract (Mentha spicata) (aerial parts) and Green Tea Extract (Camellia sinensis)(leaves)Ā | |
| Ashwagandha extract (Withania somnifera) (roots and leaves) (35% withanolide glycosides)Ā | 120 mgĀ |
Other Ingredients: Capsule (hypromellose and water), ascorbyl palmitate, and silica.Ā
Does Not Contain: Dairy, egg, gluten, shellfish, soy, tree nuts, wheat, peanuts, fish, yeast, GMOs, sesame, or animal products.Ā
Suggested Use
Take 2 capsules 30 minutes before bedtime, or use as directed by your healthcare professional.
Warning: Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if the tamper seal is damaged.
Storage:Ā Keep closed in a cool, dry place out of reach of children.
More Info.Ā
Sleep and Perform is a multifunctional formula designed to promote sleep quality and support daytime focus and concentration. It features ShodenĀ® and Daily Zzā¢, a unique combination of ingredients demonstrated to encourage restful sleep and support next-day cognitive function.
ShodenĀ®
Ashwagandha (Withania somnifera) is classified as an āadaptogenicā herb, indicating an ability to support how the body physiologically adapts. In the Ayurvedic tradition, ashwagandha is considered a rasayana,5 meaning it is used as a rejuvenator to achieve homeostasis, build vitality, and slow degenerative and senescence-related processes. For thousands of years, ashwagandha has been used to help support people with ailments ranging from musculoskeletal conditions to sleep issues. It is widely used today for restoring physical and mental energy while balancing the effects of daily stress. Analysis of ashwagandha has revealed that it contains a wide range of biologically active chemical constituents collectively known as withanolides.
Shoden is an extract derived from the leaves and roots of the ashwagandha plant. This multipatented ashwagandha extract is distinguished by its industry-leading concentration of 35% withanolide glycosides. Shoden has been evaluated for its adaptogenic role in the stress response and for the support of restful sleep.
To ascertain the effect of Shoden on restorative sleep, healthy subjects (N = 150) were given 120 mg of Shoden daily for 6 weeks in a doubleblind, placebo-controlled study. Overall sleep quality was evaluated using a weekly questionnaire and an assessment of parameters, such as sleep latency, sleep efficiency, and total sleep time, as measured by a wearable sleep actigraphy diagnostic monitoring device. A significant improvement in sleep measures that define nonrestorative sleep was noted in the treatment group when compared with the placebo, demonstrating the positive effect of Shoden on encouraging restful sleep.
The mechanistic actions of Shoden and their potential impact on sleep were assessed using in vitro and in vivo animal model experiments. Shoden was found to have calming properties, including involvement in the induction of sleep, GABA-mimetic action, non-REM sleep patterns, and slow-wave electroencephalograph (EEG) cycles, suggesting potential for improving sleep quality.
Daily Zzā¢
Emerging evidence indicates that polyphenolic compounds in plants may have benefits for sleep quality. Epigallocatechin gallate (EGCG), a polyphenol compound found in green tea (Camellia sinensis), is well known for its demonstrated antioxidant activity. In addition, EGCG also prolongs the effects of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter that plays a role in the relaxation of the central nervous system. This occurs via positive allosteric modulation of the GABAA receptor by EGCG, resulting in enhanced GABAA sensitivity.
Rosmarinic acid, found in plants of the Lamiaceae family, such as rosemary, lemon balm, and mint, also influences GABAās neurotransmitter activity through positive allosteric modulation of the GABAA receptor. This results in a mild inhibition of glutamate, the main excitatory neurotransmitter, which may contribute to the effect of rosmarinic acid on sleep quality. In addition, rosmarinic acid from plants, including spearmint (Mentha spicata), has been reported to benefit cognitive performance and attention. An inhibitory effect on the acetylcholinesterase and butyrylcholinesterase enzymes responsible for breaking down acetylcholine, a neurotransmitter that is crucial for cognitive functions such as learning, memory, and attention, is thought to be a contributing factor.
A polyphenol-rich blend of spearmint and green tea extracts, known as Daily Zz, has been studied for its benefit to sleep quality and next-day cognitive function. In a randomized, double-blind study involving 89 subjects with subclinical sleep disturbances, participants who received 485 mg/d of Daily Zz for a 30-day trial period were assessed for improvements in sleep, mood, and neurocognitive function. Ā An improvement was noted in sleep quality, as well as the ability to fall asleep, stay asleep, and wake refreshed, as recorded by subjects in a sleep diary and with an activity tracker. Additionally, improvement was noted in next-day focus and concentration, indicating a role for improved sleep without compromising neurocognitive function.
Magnesium
Although sometimes referred to as the relaxation mineral, magnesium has a wide range of physiological functions. It is primarily known for its essential role in more than 300 enzymatic biochemical reactions that regulate diverse responses, including the transmission of nerve impulses across the central nervous system. Magnesium also plays a mechanistic role in maintaining cognitive function and is thought to benefit circadian rhythm and sleep quality; however, further study is needed to verify these actions and determine the optimal supplemental dose required to support these functions. Magnesium is widely distributed in the food supply, yet dietary surveys show that many individuals consume less than the recommended amount. This formula provides 50 mg of magnesium (as magnesium bisglycinate chelate) per serving, contributing 12% of the recommended daily value (420 mg) for adults.
Sleep and Perform combines ShodenĀ® and Daily Zzā¢, complemented by magnesium. This formula is designed to promote restful sleep and support next-day cognitive function.
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Description
Xymogen Sleep & Perform
Sleep Tonight, Function Tomorrow
Sleep & PerformĀ features ShodenĀ®, an ashwagandha extract with demonstrated benefits for supporting the restoration of sleep quality. Complemented with a proprietary blend of spearmint and green tea extract, this formula is designed to promote restful sleep and bolster daytime performance.
Key Benefits and Features:Ā
- Promotes Restful Sleep
- Supports Daytime Focus and Concentration
- Improves Sleep Quality and Next-Day Cognitive Function
Ingredients
| Serving Size: 2 Capsules | Amount/Serving |
| Magnesium (as magnesium bisglycinate chelate)Ā | 50 mg |
| Proprietary Blend | 485 mg |
| Spearmint Extract (Mentha spicata) (aerial parts) and Green Tea Extract (Camellia sinensis)(leaves)Ā | |
| Ashwagandha extract (Withania somnifera) (roots and leaves) (35% withanolide glycosides)Ā | 120 mgĀ |
Other Ingredients: Capsule (hypromellose and water), ascorbyl palmitate, and silica.Ā
Does Not Contain: Dairy, egg, gluten, shellfish, soy, tree nuts, wheat, peanuts, fish, yeast, GMOs, sesame, or animal products.Ā
Suggested Use
Take 2 capsules 30 minutes before bedtime, or use as directed by your healthcare professional.
Warning: Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if the tamper seal is damaged.
Storage:Ā Keep closed in a cool, dry place out of reach of children.
More Info.Ā
Sleep and Perform is a multifunctional formula designed to promote sleep quality and support daytime focus and concentration. It features ShodenĀ® and Daily Zzā¢, a unique combination of ingredients demonstrated to encourage restful sleep and support next-day cognitive function.
ShodenĀ®
Ashwagandha (Withania somnifera) is classified as an āadaptogenicā herb, indicating an ability to support how the body physiologically adapts. In the Ayurvedic tradition, ashwagandha is considered a rasayana,5 meaning it is used as a rejuvenator to achieve homeostasis, build vitality, and slow degenerative and senescence-related processes. For thousands of years, ashwagandha has been used to help support people with ailments ranging from musculoskeletal conditions to sleep issues. It is widely used today for restoring physical and mental energy while balancing the effects of daily stress. Analysis of ashwagandha has revealed that it contains a wide range of biologically active chemical constituents collectively known as withanolides.
Shoden is an extract derived from the leaves and roots of the ashwagandha plant. This multipatented ashwagandha extract is distinguished by its industry-leading concentration of 35% withanolide glycosides. Shoden has been evaluated for its adaptogenic role in the stress response and for the support of restful sleep.
To ascertain the effect of Shoden on restorative sleep, healthy subjects (N = 150) were given 120 mg of Shoden daily for 6 weeks in a doubleblind, placebo-controlled study. Overall sleep quality was evaluated using a weekly questionnaire and an assessment of parameters, such as sleep latency, sleep efficiency, and total sleep time, as measured by a wearable sleep actigraphy diagnostic monitoring device. A significant improvement in sleep measures that define nonrestorative sleep was noted in the treatment group when compared with the placebo, demonstrating the positive effect of Shoden on encouraging restful sleep.
The mechanistic actions of Shoden and their potential impact on sleep were assessed using in vitro and in vivo animal model experiments. Shoden was found to have calming properties, including involvement in the induction of sleep, GABA-mimetic action, non-REM sleep patterns, and slow-wave electroencephalograph (EEG) cycles, suggesting potential for improving sleep quality.
Daily Zzā¢
Emerging evidence indicates that polyphenolic compounds in plants may have benefits for sleep quality. Epigallocatechin gallate (EGCG), a polyphenol compound found in green tea (Camellia sinensis), is well known for its demonstrated antioxidant activity. In addition, EGCG also prolongs the effects of GABA (gamma-aminobutyric acid), an inhibitory neurotransmitter that plays a role in the relaxation of the central nervous system. This occurs via positive allosteric modulation of the GABAA receptor by EGCG, resulting in enhanced GABAA sensitivity.
Rosmarinic acid, found in plants of the Lamiaceae family, such as rosemary, lemon balm, and mint, also influences GABAās neurotransmitter activity through positive allosteric modulation of the GABAA receptor. This results in a mild inhibition of glutamate, the main excitatory neurotransmitter, which may contribute to the effect of rosmarinic acid on sleep quality. In addition, rosmarinic acid from plants, including spearmint (Mentha spicata), has been reported to benefit cognitive performance and attention. An inhibitory effect on the acetylcholinesterase and butyrylcholinesterase enzymes responsible for breaking down acetylcholine, a neurotransmitter that is crucial for cognitive functions such as learning, memory, and attention, is thought to be a contributing factor.
A polyphenol-rich blend of spearmint and green tea extracts, known as Daily Zz, has been studied for its benefit to sleep quality and next-day cognitive function. In a randomized, double-blind study involving 89 subjects with subclinical sleep disturbances, participants who received 485 mg/d of Daily Zz for a 30-day trial period were assessed for improvements in sleep, mood, and neurocognitive function. Ā An improvement was noted in sleep quality, as well as the ability to fall asleep, stay asleep, and wake refreshed, as recorded by subjects in a sleep diary and with an activity tracker. Additionally, improvement was noted in next-day focus and concentration, indicating a role for improved sleep without compromising neurocognitive function.
Magnesium
Although sometimes referred to as the relaxation mineral, magnesium has a wide range of physiological functions. It is primarily known for its essential role in more than 300 enzymatic biochemical reactions that regulate diverse responses, including the transmission of nerve impulses across the central nervous system. Magnesium also plays a mechanistic role in maintaining cognitive function and is thought to benefit circadian rhythm and sleep quality; however, further study is needed to verify these actions and determine the optimal supplemental dose required to support these functions. Magnesium is widely distributed in the food supply, yet dietary surveys show that many individuals consume less than the recommended amount. This formula provides 50 mg of magnesium (as magnesium bisglycinate chelate) per serving, contributing 12% of the recommended daily value (420 mg) for adults.
Sleep and Perform combines ShodenĀ® and Daily Zzā¢, complemented by magnesium. This formula is designed to promote restful sleep and support next-day cognitive function.
